PDF OnlyMyoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.Alejandro, D S; Petersen, J Author Information Division of Nephrology, Stanford University School of Medicine, CA 94305-5114. Journal of the American Society of Nephrology : JASN 5(2):p 153-160, August 1994. | DOI: 10.1681/ASN.V52153 Free Metrics Abstract Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors is reviewed. The potential mechanisms of myoglobinuria and nephrotoxicity and the therapeutic implications are discussed. Copyright © 1994 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.
