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Effects of Aerobic and Resistance Exercise on Cardiovascular Parameters for People Living With HIV

A Meta-analysis

Zech, Philipp, Dipl*; Pérez-Chaparro, Camilo, MD; Schuch, Felipe, PhD; Wolfarth, Bernd, MD, PhD; Rapp, Michael, MD, PhD; Heissel, Andreas, PhD

Journal of the Association of Nurses in AIDS Care: March-April 2019 - Volume 30 - Issue 2 - p 186–205
doi: 10.1097/JNC.0000000000000006
Research Article
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People living with HIV (PLWH) have limited exercise capacity because of anemia, neuromuscular disorders, and pulmonary limitations. We used a meta-analysis to examine the effect of aerobic and resistance exercise alone and in combination on cardiovascular parameters. Subgroup meta-analyses were conducted and long-term effects of exercise were investigated. A systematic literature search was conducted up to July/August 2017. The Physiotherapy Evidence Database-scale was used to rate quality and assess the risk of bias on the papers. Standardized mean differences (SMDs) were calculated to assess the effect of exercise. Posttreatment comparison between the exercise and control groups revealed moderate and large effect sizes in favor of the intervention group for VO2max (SMD = 0.66, p < .0001) and the 6-minute walk test (SMD = 1.11, p = .0001). Exercise had a positive effect on cardiovascular parameters in PLWH. Exercise can be a prevention factor for PLWH dealing with multiple comorbidities.

Philipp Zech, Dipl, is a PhD Student and Sport Scientist, Social and Preventive Medicine, Department of Exercise and Health Sciences, University of Potsdam, Potsdam, Germany. Camilo Pérez-Chaparro, MD, is a Physician in Sport Medicine and PhD Student, Post Graduate Program in Health and Human Development, La Salle University, Canos, Brazil. Felipe Schuch, PhD, is a Professor and Sport Scientist, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Bernd Wolfarth, MD, PhD, is Professor and Physician in Sport Medicine, Department of Sports Sciences, Division of Sports Medicine, Humboldt University of Berlin, Berlin, Germany. Michael Rapp, MD, PhD, is Professor and Physician in Psychiatry, Social and Preventive Medicine, Department of Exercise and Health Sciences, University of Potsdam, Potsdam, Germany. Andreas Heissel, PhD, is a Research Fellow and Sports Scientist, Social and Preventive Medicine, Department of Exercise and Health Sciences, University of Potsdam, Potsdam, Germany.

Corresponding author: Philipp Zech, e-mail: phzech@uni-potsdam.de

Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article

© 2019 Association of Nurses in AIDS Care
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