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NEU Screen Shows High Accuracy in Detecting Cognitive Impairment in Older Persons Living With HIV

Prats, Anna, MS; López-Masramon, Estela, MS; Pérez-Álvarez, Núria, PhD; Garolera, Maite, PhD; Fumaz, Carmina R., PhD; Ferrer, Maria J., MS; Clotet, Bonaventura, PhD; Muñoz-Moreno, Jose A., PhD*

Journal of the Association of Nurses in AIDS Care: January-February 2019 - Volume 30 - Issue 1 - p 35–41
doi: 10.1097/JNC.0000000000000003
Research Article
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The NEUrocognitive (NEU) Screen is a practical tool proposed to screen for HIV-associated cognitive impairment in the clinical setting. This is a pencil-and-paper method that can be applied rapidly (≤10 minutes for administration) and has no copyright limitations. In this study, we aimed at investigating its diagnostic accuracy in an older population of persons living with HIV (PLWH), with cutoffs set at 30, 40, 50, and 60 years. Data were collected from a sample of 368 PLWH who underwent a comprehensive neuropsychological tests battery (gold standard). Results of statistical tests showed that accuracy of the NEU Screen increased with age of the participants. The highest degree of precision, with a sensitivity of 91% and specificity of 92%, was obtained for people ages 60 years or older (correct classification: 91%). These optimal results point to the great potential of the NEU Screen as a tool for detecting cognitive disorders in older PLWH.

Anna Prats, MS, is Neuropsychologist, Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain; and Doctoral Candidate, Departament de Psiquiatria i Medicina Legal, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Catalonia, Spain. Estela López-Masramon, MS, is Neuropsychologist, Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain. Núria Pérez-Álvarez, PhD, is Statistician, Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain; and Assistant Professor, Universitat Politècnica de Catalunya, Barcelona, Catalonia, Spain. Maite Garolera, PhD, is Neuropsychologist, Clinical Research Group for Brain, Cognition and Behavior, Consorci Sanitari Hospital de Terrassa, Terrassa, Catalonia, Spain; and Senior Researcher, Grup de Recerca Consolidat en Neuropsicologia, Universitat de Barcelona, Barcelona, Catalonia, Spain. Carmina R. Fumaz, PhD, is Psychologist, Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain. Maria J. Ferrer, MS, is Psychologist, Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain. Bonaventura Clotet, PhD, is Physician, Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain; Senior Researcher, Institut per la Recerca de la SIDA, IrsiCaixa Badalona, Catalonia, Spain; and Professor, Universitat de Vic, Vic, Catalonia, Spain. Jose A. Muñoz-Moreno, PhD, is Psychologist, Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain; and Assistant Professor, Facultat de Psicologia i Ciències de l'Educació, Universitat Oberta de Catalunya, Barcelona, Catalonia, Spain.

Corresponding author: Jose A. Muñoz-Moreno, e-mail: jmunoz@flsida.org

Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

Preliminary results of the work have been presented in the 14th International Symposium on Neurovirology, October 25–28, 2016, Toronto, Ontario, Canada (Abstract P114).

© 2019 Association of Nurses in AIDS Care
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