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Computerized Cognitive Training for the Neurocognitive Complications of HIV Infection

A Systematic Review

Vance, David E., PhD, MGS*; Fazeli, Pariya L., PhD; Cheatwood, John, MSN, CRNP, PMHNP-BC, RN; Nicholson, W. Chance, MSN, PMHNP-BC; Morrison, Shannon A., PhD, RN; Moneyham, Linda D., PhD, RN, FAAN

Journal of the Association of Nurses in AIDS Care: January-February 2019 - Volume 30 - Issue 1 - p 51–72
doi: 10.1097/JNC.0000000000000030
Research Article
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The synergistic effects of HIV and aging on the brain may compromise cognitive reserve, resulting in HIV-associated neurocognitive disorder. The neuroscience literature suggests that computerized cognitive training programs represent a practical strategy to protect or remediate cognitive functioning in older adults. Such cognitive training programs may hold similar therapeutic benefits for adults living with HIV. This systematic review evaluated the effects of cognitive training interventions in adults living with HIV. This systematic review includes 13 studies that have been conducted or are being conducted. Results suggest that cognitive training may improve the cognitive domain that is the target of training. One case study even demonstrated a reversal of HIV-associated neurocognitive disorder after cognitive training. Although greater evidence is needed to establish treatment guidelines, current evidence suggests that cognitive training improves cognitive function, which translates to more optimal everyday functioning (i.e., driving), improved mood, greater locus of control, and enhanced quality of life.

David E. Vance, PhD, MGS, is a Professor and Interim Associate Dean for Research, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA. Pariya L. Fazeli, PhD, is an Assistant Professor, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA. John Cheatwood, MSN, CRNP, PMHNP-BC, RN, is a PhD Student, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA. Chance Nicholson, MSN, PMHNP-BC, is a PhD Student, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA. Shannon Morrison, PhD, RN, is an Associate Professor, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA. Linda D. Moneyham, PhD, RN, FAAN, is a Professor & Senior Associate Dean of Academic Affairs, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Corresponding author: David E. Vance, e-mail: devance@uab.edu

Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

© 2019 Association of Nurses in AIDS Care
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