FeatureThe Symptom Experience of HIV/HCV-Coinfected AdultsBova, Carol, PhD, RN, ANP; Jaffarian, Carol, MS, RN, ANP; Himlan, Pauline, MEd, RN, FNP; Mangini, Linda, MS, RN, ANP; Ogawa, Lisa, PhD, RNAuthor Information Carol Bova, PhD, RN, ANP, is an associate professor at the University of Massachusetts Graduate School of Nursing, Worcester. Carol Jaffarian, MS, RN, ANP, is an instructor at the University of Massachusetts Graduate School of Nursing. Pauline Himlan, MEd, RN, FNP, is a nurse practitioner at UMass Memorial Health Care, Worcester. Linda Mangini, MS, RN, ANP, is a nurse practitioner at UMass Memorial Health Care. Lisa Ogawa, PhD, RN, is a research assistant at the University of Massachusetts Graduate School of Nursing. Journal of the Association of Nurses in AIDS Care: May 2008 - Volume 19 - Issue 3 - p 170–180 Buy Abstract Hepatitis C virus (HCV) infection has emerged as a major problem for adults with HIV infection. This report describes the symptom experience of HIV/HCV-coinfected adults at entry into a longitudinal mixed-method study. In-depth qualitative interviews and a standardized quantitative symptom measure were used to capture the symptom experiences of 39 (46% women) HIV/HCV-coinfected patients. Four major themes emerged from the qualitative interviews: (a) difficulty differentiating between HIV and HCV-related symptoms, (b) commonly cited HCV-related symptoms, (c) ways to control or manage HCV-related symptoms, and (d) lack of symptoms or tests to monitor HCV disease. Participants reported an average of 10 different symptoms and a mean symptom experience score of 18.33 (range = 2-47). Results show the significant symptom burden experienced by HIV/HCV-coinfected adults. However, results suggest that the prevalence of symptoms for HIV/HCV-coinfected patients may not be greater than those experienced by patients with HIV infection alone. © 2008Elsevier, Inc.