Letters to the EditorPatient-Derived HIV-1 Nef Alleles Reveal Uncoupling of CD4 Downregulation and SERINC5 Antagonism Functions of the Viral Pathogenesis FactorObermaier, Benedikta,b; Ananth, Swetha MSca,b; Tibroni, Nadine BSca; Pierini, Virginia MSca; Shytaj, Iart L. PhDa,b; Diaz, Ricardo S. MD, PhDc; Lusic, Marina PhDa,b; Fackler, Oliver T. PhDa,bAuthor Information aDepartment of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany bGerman Centre for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany cInfectious Diseases Department, Federal University of Sao Paulo, São Paulo, Brazil Supported by the German Center for Infection Research (DZIF) (Grant TTU 04.810, an Integrated Approach for HIV-Cure “Shock and Kill” Strategies to O.T.F.; Grant DZIF TI 07.003—FP2016 MD Program to B.O.), the Deutsche Forschungsgemeinschaft (Grant FA 378/17-1 to O.T.F.) and the Humboldt Foundation (scholarship Ref 3.3—ITA—1193954—HFST-P to I.L.S.). The authors have no conflicts of interest to disclose. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jaids.com). JAIDS Journal of Acquired Immune Deficiency Syndromes: October 1, 2020 - Volume 85 - Issue 2 - p e23-e26 doi: 10.1097/QAI.0000000000002418 Buy SDC Metrics Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.