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Neurosyphilis During Acute HIV Infection

A CNS Immunologic and Virologic Characterization

Chan, Phillip MBChBa; Dumrongpisutikul, Netsiri MDb; Subra, Caroline PhDc,d; Colby, Donn J. MDa; Kroon, Eugène MDa; Fletcher, James MDa; Sacdalan, Carlo MDa; Phanuphak, Nittaya MDa; Valcour, Victor MDe; Ananworanich, Jintanat MDa,c,d,f; Trautmann, Lydie PhDc,d; Spudich, Serena MDg

JAIDS Journal of Acquired Immune Deficiency Syndromes: October 1, 2019 - Volume 82 - Issue 2 - p e34–e37
doi: 10.1097/QAI.0000000000002114
Letters to the Editor
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aSEARCH, Thai Red Cross AIDS Research Centre, Bangkok, Thailand

bDepartment of Radiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

cThe Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD

dU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD

eDepartment of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA

fDepartment of Global Health, University of Amsterdam, Amsterdam, the Netherlands

gDepartment of Neurology, Yale University School of Medicine, New Haven, CT

J.A. has received honoraria for participating in advisory meetings for ViiV Healthcare, Merck, Gilead, Roche, and AbbVie. V.V. reports grants from NIH, other from UCSF, during the conduct of the study; personal fees from ViiV Healthcare, personal fees from Merck, outside the submitted work. S.S. reports grants from NIH—NIMH & NINDS, during the conduct of the study; nonfinancial support from ViiV Healthcare, Inc., outside the submitted work. J.F. reports other from Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., and the U.S. Department of Defense (DoD), during the conduct of the study. L.T. reports grants from NIH—NIMH, during the conduct of the study. The remaining authors have no conflicts of interest to disclose.

All authors have contributed to and approved the manuscript.

Ethics approval and consent to participate and consent for publication: The case report is based on the research findings from one of the participants in RV254/SEARCH010 study (clinicaltrials.gov NCT00796146). The participant provided written informed consent to participate in the study. The study protocol was approved by the institutional review boards of Chulalongkorn University, Bangkok, Thailand; the Walter Reed Army Institute of Research, Silver Spring, MD; University of California, San Francisco, CA; and Yale University, New Haven, CT.

The views expressed are those of the authors and should not be construed to represent the positions of the U.S. Army, the Department of Defense. The investigators have adhered to the policies for protection of human subjects as prescribed in AR-70.

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