Departments of aEmergency Medicine; and
bInformatics, University of California, Irvine, Irvine, CA; and
Departments of cBiostatistics; and
dMedicine, University of California, Los Angeles, Los Angeles, CA.
Correspondence to: Sean Young, PhD, MS, Departments of Emergency Medicine and Informatics, University of California, Irvine, 6091 Bren Hall, Irvine, CA 92617 (e-mail: [email protected]).
Supported by funding from the National Institute of Mental Health (NIMH 5R01MH106415) and National Center for Complementary and Integrative Health (NCCIH). The funding agency played no role in study design, analysis, or manuscript.
S.Y. is on the board within the Health and Medicine Division of the National Academies of Sciences, Engineering, and Medicine to advise on STI-related research and policy; S.Y. is an advisor to digital health startups, including ElevateU, which helps substance use and HIV researchers conduct online studies. The remaining authors have no conflicts of interest to disclose.
S.Y. conceived of and conducted the study and wrote the manuscript; W.G.C. senior statistician, participated in study design and sample size calculations, reviewed and revised the manuscript, and was responsible for estimation of effects; P.S. postdoctoral scholar, conducted data management, data analysis and reviewed, and revised the manuscript; and T.C.: advised on study and reviewed the manuscript.
ClinicalTrials.gov identifier: NCT02944877 (completed).
Reproducible research statement—Statistical code and data set: not available. Study protocol: available from S. Young on request.