aDepartment of Internal Medicine, Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands;
bSynapse Research Institute, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands; and
cDepartment for Genomics and Immunoregulation, Life and Medical Sciences 12 Institute (LIMES), University of Bonn, Bonn, Germany.
Correspondence to: Wouter A. van der Heijden, MD, Department of Internal Medicine, Radboud University Medical Center, 6500 HB Nijmegen, Netherlands (e-mail: [email protected]).
Supported in part by an AIDS-fonds Netherlands Grant. M.G.N. was supported by a Spinoza grant of the Netherlands Organization for Scientific Research and an ERC Advanced Grant (#833247). J.W. was supported by a scholarship (No. 201606130068) from the China Scholarship Council. All contributors were not involved in the study design, data interpretation, or the submission.
M.R. is employed by Synapse Research Institute, which is a member of the Stago group. The other authors have no funding or conflicts of interest to disclose.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.jaids.com).
W.A.H, Q.M., M.R., and A.J.V. designed the study. W.A.H., L.V.W., and M.J. recruited and included the participants. W.A.H., J.W., and L.W. performed the laboratory experiments. W.A.H. and J.W. analyzed the data and interpreted the data together with Q.M., P.G.G., M.R., and A.J.V. W.A.H., J.W., A.J.V., and Q.M. wrote the manuscript. All authors have read and contributed significantly to the final manuscript.
