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Characteristics and Care Outcomes Among Persons Living With Perinatally Acquired HIV Infection in the United States, 2015

Gray, Kristen Mahle MPHa; Wang, Xiao MPHb; Li, Jianmin DPEa; Nesheim, Steven R. MDa

JAIDS Journal of Acquired Immune Deficiency Syndromes: September 1, 2019 - Volume 82 - Issue 1 - p 17–23
doi: 10.1097/QAI.0000000000002091
Epidemiology
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Background: Medical advancements have improved the survival of persons with perinatally acquired HIV infection (PHIV). We describe persons living with diagnosed PHIV and assess receipt of HIV care, retention in care, and viral suppression.

Methods: Data reported to the National HIV Surveillance System through December 2017 were used to characterize persons living with diagnosed PHIV by year-end 2015 in the United States and 6 dependent areas. National HIV Surveillance System data from 40 jurisdictions with complete laboratory reporting were used to assess receipt of HIV care (≥1 CD4 or viral load during 2015), retention in HIV care (≥2 CD4 or viral load tests ≥3 months apart during 2015) and viral suppression (<200 copies/mL during 2015) among persons with PHIV diagnosed by year-end 2014 and alive at year-end 2015.

Results: By year-end 2015, 11,747 persons were living with PHIV and half were aged 18–25 years. Of 9562 persons with HIV diagnosed by year-end 2014 and living with PHIV at year-end 2015 in the 40 jurisdictions, 75.4% received any care, 61.1% were retained in care, and 49.0% achieved viral suppression. Persons aged ≤17 years had a significantly higher prevalence of being retained in care (prevalence ratio = 1.2, 95% confidence interval = 1.2 to 1.3) and virally suppressed (prevalence ratio = 1.4, 95% confidence interval = 1.3 to 1.5) than persons aged 18–25 years.

Conclusions: Efforts to improve care outcomes among persons with PHIV are needed. Enhanced collaboration between pediatric and adult medical providers may ensure continuity of care during the transition from adolescence to adulthood.

aDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA; and

bICF, Atlanta, GA.

Correspondence to: Kristen M. Gray, MPH, Centers for Disease Control and Prevention, 1600 Clifton Road, Northeast Atlanta, GA 30333 (e-mail: KGray1@cdc.gov).

The authors have no conflicts of interest to disclose.

The findings and conclusions in this manuscript are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention (CDC). The use of trade names and commercial sources is for identification only and does not imply endorsement by CDC.

Received December 29, 2018

Accepted April 18, 2019

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.