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Food Insecurity and CD4% Among HIV+ Children in Gaborone, Botswana

Mendoza, Jason A. MD, MPH*,†; Matshaba, Mogomotsi MB, BCh, BAO, BMedSci‡,§; Makhanda, Jeremiah MSc; Liu, Yan MS; Boitshwarelo, Matshwenyego MD; Anabwani, Gabriel M. MBChB, MMed, MSCE, FRCPE‡,§

JAIDS Journal of Acquired Immune Deficiency Syndromes: August 1st, 2014 - Volume 66 - Issue 4 - p 414–418
doi: 10.1097/QAI.0000000000000190
Brief Report: Clinical Science

Abstract: We investigated the association between household food insecurity (HFI) and CD4% among 2–6-year old HIV+ outpatients (n = 78) at the Botswana-Baylor Children's Clinical Center of Excellence in Gaborone, Botswana. HFI was assessed by a validated survey. CD4% data were abstracted from the medical record. We used multiple linear regression with CD4% (dependent variable), HFI (independent variable), and controlled for sociodemographic and clinical covariates. Multiple linear regression showed a significant main effect for HFI [beta = −0.6, 95% confidence interval (CI): −1.0 to −0.1] and child gender (beta = 5.6, 95% CI: 1.3 to 9.8). Alleviating food insecurity may improve pediatric HIV outcomes in Botswana and similar Sub-Saharan settings.

*General Pediatrics, Department of Pediatrics, University of Washington, Seattle, WA;

Center for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA;

Botswana-Baylor Children's Clinical Center of Excellence, Gaborone, Botswana; and

§Retrovirology and

Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX.

Correspondence to: Jason A. Mendoza, MD, MPH, Seattle Children's Research Institute, PO Box 5371, Suite 400, M/S: CW8-6, Seattle, WA 98145-5005 (e-mail:

Research reported in this publication was supported, in part, by a career development award to the first author while at the Children's Nutrition Research Center of Baylor College of Medicine from the National Cancer Institute of the National Institutes of Health under award No. K07CA131178. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders or the authors' affiliated academic institutions. The funders had no role in the design, collection, analysis, and interpretation of data or writing/submission of this report.

The authors have no conflicts of interest to disclose.

Received November 21, 2013

Accepted March 26, 2014

© 2014 by Lippincott Williams & Wilkins