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Halima Myriam Ben; Pasquier, Christophe; Slim, Amine; Chaabane, Taoufik Ben; Arrouji, Zakia; Puel, Jacqueline; Redjeb, Saida Ben; Izopet, Jacques
JAIDS Journal of Acquired Immune Deficiency Syndromes: September 1st, 2001
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In order to identify HIV-1 subtypes circulating in Tunisia, blood specimens from 25 HIV-1 nfected Tunisian patients were collected. Proviral HIV-1 DNA was genotyped by sequence analysis of the C2-V3 env region. HIV-1 subtypes were determined in 21 DNA sequences: 20 were of subtype B and one was a circulating recombinant form (CRF02 AG).Subtype B largely dominates the epidemiology of HIV-1 infection in Tunisia, suggesting the probable imported origin of HIV-1 infection, but further studies are needed to investigate the potential diversification of HIV-1 isolates in Tunisia.

Address correspondence and reprint requests to Christophe Pasquier, Laboratoire de Virologie, Hôpital Purpan, Place Baylac, 31059 Toulouse Cedex, France; e-mail: cpasquie@cict.fr

Manuscript received January 8, 2001; accepted June 1, 2001.

© 2001 Lippincott Williams & Wilkins, Inc.