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Sex- and Drug-Related Risk Among Populations of Younger and Older Injection Drug Users in Adjacent Neighborhoods in San Francisco

Kral Alex H.; Lorvick, Jennifer; Edlin, Brian R.
JAIDS Journal of Acquired Immune Deficiency Syndromes: June 1st, 2000
Articles: PDF Only

Summary:The objective of this study was to compare drug injection- and sex-related risk behaviors of younger and older injection drug users (IDUs) in two adjacent neighborhoods. IDUs were recruited from street settings in two adjacent neighborhoods in San Francisco in April, 1997. All participants were interviewed using a standardized questionnaire and were tested for HIV antibodies. Drug injection- and sex-related risk behaviors were compared between younger IDUs (<30 years; n = 56) and older IDUs (≥30 years; n = 116). Younger IDUs were more likely to be white, be homeless, have injected amphetamines, and have been arrested in the past year. Older IDUs were more likely to be African American and smoke crack cocaine; they had injected a mean of 18 years longer. Younger IDUs were more likely to have shared syringes in the past month (52% versus 10%; p < .05), report drug overdose in the past 15 months (39% versus 7%; p < .05), and to have had unprotected vaginal intercourse in the past 6 months (77% versus 53%; p < .05). After controlling for confounding factors using logistic regression analysis, all these associations remained significant. There is an urgent need for innovative prevention programs that target younger, homeless IDUs.

Address correspondence and reprint requests to Alex H. Kral, Urban Health Study, University of California, San Francisco, 3180 18th Street, Suite 302, San Francisco, CA 94110, U.S.A.; email:

Manuscript received November 17, 1999; accepted February 29, 2000.

© 2000 Lippincott Williams & Wilkins, Inc.