Summary:Trends in the vertical transmission rate of HIV and evolving antiretroviral usage between 1990 and 1998 within the Women and Infants Transmission Study were evaluated. A decline in mother-infant transmission was temporally associated with advances in therapy, especially when regimens including a protease inhibitor were included in the analysis.
Address correspondence and reprint requests to Ellen R. Cooper, Pediatric AIDS Program. Boston Medical Center, 774 Albany Street, 5th Floor, Boston, MA 02118-2393, U.S.A.
Manuscript received December 13, 1999; accepted February 16, 2000.
© 2000 Lippincott Williams & Wilkins, Inc.