Case ReportPiecing together the subtle clues of common variable immunodeficiencyKochanoff, Kimberly DeVore MS, PA-C Author Information Kimberly DeVore Kochanoff is director of clinical education and an assistant professor at Arizona School of Health Sciences in Mesa, Ariz., and a student in the doctor of medical science program at A.T. Still University. The author has disclosed no potential conflicts of interest, financial or otherwise. JAAPA 36(6):p 23-26, June 2023. | DOI: 10.1097/01.JAA.0000923544.76902.f9 Buy Metrics Abstract Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder that results in decreased immunity and increased infection risk. This multisystem disorder often presents as recurrent, prolonged respiratory tract infections. Other manifestations include chronic lung disease, systemic granulomatous disease, malignancies, enteropathy, splenomegaly, and autoimmune disease including cytopenias. Diagnosis often is delayed, affecting patient quality of life, morbidity, and mortality. This article reviews the presentation, diagnosis, and management of patients with CVID. Copyright © 2023 American Academy of Physician Associates
