Case ReportProgression of a Buschke-Lowenstein tumor into invasive squamous cell carcinomaFai, Emmanuel K. PA-C, PhD; Bhutta, Habib A. MD; Ali, Kashif MD Author Information Emmanuel K. Fai practices in the Department of Neuroscience at the University of Maryland Medical Center Midtown Campus and in the Department of General Surgery at Laurel Regional Hospital in Laurel, Md. Habib A. Bhutta is a general surgeon in the Department of General Surgery and Kashif Ali is an oncologist in the Department of Medicine at Laurel Regional Hospital. The authors have disclosed no potential conflicts of interest, financial or otherwise. Journal of the American Academy of Physician Assistants: June 2019 - Volume 32 - Issue 6 - p 1-4 doi: 10.1097/01.JAA.0000554740.24182.ae Buy Metrics Abstract Buschke-Lowenstein tumors primarily are slow-growing giant condylomata accuminata of the anogenital region. They are locally destructive with a low rate of metastasis. Sexually transmitted oncogenic human papillomavirus type 6 and 11 are the greatest risk factors for Buschke-Lowenstein tumors or verrucous carcinomas, a type of squamous cell cancer. Grossly, the tumor appears as a large fungating, erythematous, cauliflower-like mass. Radical surgical excision of the tumor is the treatment of choice and close follow-up for recurrence is essential. The use of radiation or chemotherapy as adjunct treatments is controversial. This case report describes a patient with this rare condition. Copyright © 2019 American Academy of Physician Assistants
