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The effects of probiotics on mood and emotion

Kane, Lindsey; Kinzel, Julie, MEd, PA-C, DFAAPA

Journal of the American Academy of PAs: May 2018 - Volume 31 - Issue 5 - p 1–3
doi: 10.1097/01.JAA.0000532122.07789.f0
Review Article

ABSTRACT Preliminary research in humans and rodents demonstrates that various probiotic formulations of Lactobacillus and Bifidobacterium have a clinical and neurochemical anxiolytic effect on the central nervous system (CNS). Further research is warranted to more extensively examine the theorized connection between the gastrointestinal tract and the CNS; however, initial evidence suggests probiotics affect various mechanisms of the gut-brain connection that modulate anxiety-like behaviors. This article describes the wider-reaching effects of probiotics, specifically related to behavior and brain function.

At the time this article was written, Lindsey Kane was a student in the PA program at Drexel University in Philadelphia, Pa. Julie Kinzel is an assistant clinical professor in the PA program at Drexel University. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Copyright © 2018 American Academy of Physician Assistants
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