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Are hormonal contraceptives less effective in overweight and obese women?

Patel, Shriya, PharmD; Carey, Lawrence, PharmD

Journal of the American Academy of PAs: January 2018 - Volume 31 - Issue 1 - p 11–13
doi: 10.1097/01.JAA.0000527709.23569.dc
Pharmacology Consult

ABSTRACT Loss of efficacy of hormonal contraceptives is of particular concern for women who are overweight or obese. Only recently have clinical trials started to include overweight and obese women in their study populations, limiting the data available on which to make the best prescribing decisions for hormonal contraceptives for these patients. Other methods, such as the copper or levonorgestrel-containing intrauterine device, the etonogestrel implant, and depot medroxyprogesterone acetate, are preferred over combined oral contraceptives, the transdermal patch, and the vaginal ring.

At the time this article was written, Shriya Patel was a student in the doctor of pharmacy program at Temple University School of Pharmacy in Philadelphia, Pa. She is now a medical writer at Springer Healthcare in Philadelphia. Lawrence Carey is a clinical professor in the Temple University School of Pharmacy and a lecturer in pharmacotherapeutics and former director of the PA program at Philadelphia University (now Thomas Jefferson University) in Philadelphia, Pa. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Mary Lou Brubaker, PharmD, PA-C, department editor

Copyright © 2018 American Academy of Physician Assistants
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