Rapid cognitive and functional decline: Creutzfeldt-Jakob diseaseDameron, Matthew MPAS, PA-CJournal of the American Academy of Physician Assistants: September 2013 - Volume 26 - Issue 9 - p doi: 10.1097/01.JAA.0000433963.28385.db Case Report Abstract Author Information ABSTRACT The emergence of “mad cow disease” has sparked interest in prion diseases, including Creutzfeldt-Jakob disease, a spongiform encephalopathy that can mimic other rapidly progressive dementias. A systematic approach to evaluation and diagnostic testing can help rule out other causes. Matthew Dameron practices internal medicine in Roanoke, Virginia. The author has indicated no relationships to disclose relating to the content of this article. © 2013 American Academy of Physician Assistants.