Sickle cell disease: Taking a multidisciplinary approachApanah, Stephanie RPA-C; Rizzolo, Denise PhD, PA-CJournal of the American Academy of Physician Assistants: August 2013 - Volume 26 - Issue 8 - p 28–33 doi: 10.1097/01.JAA.0000432497.24151.d4 Hematology Abstract Author Information ABSTRACT A costly major public health concern, sickle cell disease (SCD) affects up to 100,000 Americans and can cause life-threatening complications. This article reviews the pathophysiology, signs and symptoms, diagnostic testing, management, and treatment of patients with SCD. Stephanie Apanah practices in the ED at Beth Israel Medical Center in New York City. She completed an emergency medicine residency at Weill Cornell Medical Center in New York City. Denise Rizzolo is an assistant clinical professor in the PA program at Pace University and an associate professor in the Seton Hall University PA program in South Orange, New Jersey. The authors have indicated no relationships to disclose relating to the content of this article. Earn Category I CME Credit by reading this article and the article beginning on page 20 and successfully completing the posttest on page 34. Successful completion is defined as a cumulative score of at least 70% correct. This material has been reviewed and is approved for 1 hour of clinical Category I (Preapproved) CME credit by the AAPA. The term of approval is for 1 year from the publication date of August 2013. © 2013 American Academy of Physician Assistants.