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A Comparison of Limb Salvage Versus Amputation for Nonmetastatic Sarcomas Using Patient-reported Outcomes Measurement Information System Outcomes

Wilke, Benjamin, MD; Cooper, Anna, MD, MPH; Scarborough, Mark, MD; Gibbs, Parker, MD; Spiguel, Andre, MD

JAAOS - Journal of the American Academy of Orthopaedic Surgeons: April 15, 2019 - Volume 27 - Issue 8 - p e381–e389
doi: 10.5435/JAAOS-D-17-00758
Research Article

Introduction: The Patient-reported Outcomes Measurement Information System (PROMIS) is a scoring tool that allows comparisons between patients with rare conditions and more common ailments, or the general US population. PROMIS outcomes were compared between the limb salvage and amputee patients for nonmetastatic sarcomas to the US population.

Methods: One hundred thirty-eight patients were included in the analysis. Patients were divided into the limb salvage and amputee cohorts, as well as based on the follow-up (1 to 11 or 12+ months).

Results: Seven PROMIS domains were evaluated, and higher scores were found in both the limb salvage group and patients >12 months from surgery. The limb salvage group also had improved emotional health compared with the US population.

Discussion: Improvements in PROMIS values are observed in limb salvage patients and in patients >12 months from surgery. Limb salvage patients demonstrate improved emotional health compared with the US population.

From the Department of Orthopedic Surgery, Mayo Clinic Florida, Jacksonville, FL (Dr. Wilke), the Department of Orthopedic Surgery, Loyola University, Maywood, IL (Dr. Cooper), and the Department of Orthopedic Surgery, University of Florida, Gainesville, FL (Dr. Scarborough, Dr. Gibbs, and Dr. Spiguel).

Correspondence to Dr. Spiguel: spiguar@ortho.ufl.edu

Dr. Scarborough or an immediate family member has received royalties from Exactech; serves as a paid consultant to Exactech; and serves as a board member, owner, officer, or committee member of the International Society of Limb Salvage. Dr. Gibbs or an immediate family member has received royalties from Exactech and serves as a paid consultant to Exactech. None of the following authors or any immediate family member has received anything of value from or has stock or stock options held in a commercial company or institution related directly or indirectly to the subject of this article: Dr. Wilke, Dr. Cooper, and Dr. Spiguel.

© 2019 by American Academy of Orthopaedic Surgeons
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