The purpose of this paper is to discover whether biological and genetic differences play an important role in the pathogenesis of developing type 2 diabetes in the African-American population
Review of original studies and meta-analyses from Medline, PubMed, CINAHL, Scopus
It is now well established that the development of type 2 diabetes results from the interaction between the individuals' biological and genetic makeup and their environment. Even though some genetic variants have been found, the full genetic landscape of type 2 diabetes, especially among African-Americans, is not yet discovered. Further researches or studies on pathophysiology and genetic susceptibility to diabetes may suggest new therapeutic targets for the treatment and prevention of insulin resistance.
Implications for practice:
as a potential cause of type 2 diabetes may suggest new therapeutic targets for the treatment and prevention, and new detecting tools for the undiagnosed patients. Nurse practitioners may gain a better understanding of the particular genetic defect influencing individual health and create the appropriate care plan to achieve an optimal health outcome for a patient.