This issue of the journal, as always, has many outstanding articles, representing cutting edge research in diagnostic imaging. More specifically, it is the second of two focused special issues concerning contrast media in diagnostic imaging. The October issue deals with topics concerning both MR and CT. The first article is a critically important review article, discussing the dechelation (transmetalation) that occurs in vivo with linear gadolinium chelates, together with the consequences and associated safety concerns, in view of the recent health care rulings across the world. Eight articles follow, five clinical MR studies, and three CT studies - one clinical and two involving potential new contrast media. The MR studies involve the liver, breast and prostate, with accelerated imaging a specific subtopic. An important statement for CT comes from an article evaluating safety guidelines, concluding that the incidences of CIN and mortality at 35 days are significantly higher in stage 4 as opposed to stage 3 chronic kidney disease.

Current Issue Highlights

Multireader Study on the Diagnostic Accuracy of Ultrafast Breast Magnetic Resonance Imaging for Breast Cancer Screening

van Zelst, Jan C.M.; Vreemann, Suzan; Witt, Hans-Joerg; More

Investigative Radiology. 53(10):579-586, October 2018.

Diffusion-Weighted Imaging With Apparent Diffusion Coefficient Mapping for Breast Cancer Detection as a Stand-Alone Parameter: Comparison With Dynamic Contrast-Enhanced and Multiparametric Magnetic Resonance Imaging

Pinker, Katja; Moy, Linda; Sutton, Elizabeth J.; More

Investigative Radiology. 53(10):587-595, October 2018.

Feasibility of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using Low-Dose Gadolinium: Comparative Performance With Standard Dose in Prostate Cancer Diagnosis

He, Dianning; Chatterjee, Aritrick; Fan, Xiaobing; More

Investigative Radiology. 53(10):609-615, October 2018.

Improved Peritoneal Cavity and Abdominal Organ Imaging Using a Biphasic Contrast Agent Protocol and Spectral Photon Counting Computed Tomography K-Edge Imaging

Si-Mohamed, Salim; Thivolet, Arnaud; Bonnot, Pierre-Emmanuel; More

Investigative Radiology. 53(10):629-639, October 2018.