The World's no. 1 Radiology journal focusing on technological advances : Investigative Radiology

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​This issue of the journal, as always, has many outstanding articles, representing cutting edge research and technology in diagnostic imaging. Critical new developments and findings in our field are presented, including that in MR, CT, and deep learning (in MR of the knee, with 8-fold acceleration). High accuracy nodal staging in head and neck cancer with USPIO-enhanced MRI is demonstrated using a new reading algorithm in a study with node-to-node matched histopathology. Advancements provided by photon-counting detector CT, including radiation dose reduction and ultra-high-resolution, are demonstrated in multiple clinical applications, including the temporal bone, the lung, and coronary CT angiography. Also highlighted is a third-generation phantom for contrast enhanced CT from the head to the toe, demonstrating the capability of simulating physiologic in vivo conditions with accurate contrast media transport timing, good repeatability, and expected enhancement profiles.

Current Issue Highlights


Potential of Photon-Counting Detector CT for Radiation Dose Reduction for the Assessment of Interstitial Lung Disease in Patients With Systemic Sclerosis

Jungblut, Lisa; Euler, André; von Spiczak, Jochen; More

Investigative Radiology. 57(12):773-779, December 2022.

High-Accuracy Nodal Staging of Head and Neck Cancer With USPIO-Enhanced MRI: A New Reading Algorithm Based on Node-to-Node Matched Histopathology

Driessen, Daphne A.J.J.; Zámecnik, Patrik; Dijkema, Tim; More

Investigative Radiology. 57(12):810-818, December 2022.