The World's no. 1 Radiology journal focusing on technological advances : Investigative Radiology

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This issue of the journal, as always, has many outstanding articles, representing cutting edge research and technology in diagnostic imaging. Critical new developments and findings in our field are presented, all within the field of magnetic resonance. Advances important for current clinical imaging are presented in 4 articles. The utility of breath-hold fat-suppressed T2-weighted images of the liver is demonstrated, using deep learning-based reconstruction, for both TSE and HASTE. Deep learning diagnosis of rotator cuff tears is shown, with excellent diagnostic performance, and model accuracy similar to subspecialty-trained musculoskeletal radiologists. Further optimization of prostate cancer assessment is demonstrated with the addition of T1 mapping using a single-shot T1 FLASH approach. And, the feasibility of single breath-hold 3D MR elastography of the liver is shown, which offers further advantages for the evaluation of nonalcoholic fatty liver disease in obese patients, which are otherwise challenging to image and which represents a global health crisis. Two additional articles examine the issue of contrast agent dose reduction in MRI using deep learning based approaches, with various pros and cons. ​

Current Issue Highlights


Usefulness of Breath-Hold Fat-Suppressed T2-Weighted Images With Deep Learning–Based Reconstruction of the Liver: Comparison to Conventional Free-Breathing Turbo Spin Echo

Ichinohe, Fumihito; Oyama, Kazuki; Yamada, Akira; More

Investigative Radiology. 58(6):373-379, June 2023.

Multimodal In Vivo Tracking of Chimeric Antigen Receptor T Cells in Preclinical Glioblastoma Models

Wu, Wei Emma; Chang, Edwin; Jin, Linchun; More

Investigative Radiology. 58(6):388-395, June 2023.

Deep Learning Diagnosis and Classification of Rotator Cuff Tears on Shoulder MRI

Lin, Dana J.; Schwier, Michael; Geiger, Bernhard; More

Investigative Radiology. 58(6):405-412, June 2023.

Single Breath-Hold 3-Dimensional Magnetic Resonance Elastography Depicts Liver Fibrosis and Inflammation in Obese Patients

Darwish, Omar Isam; Gharib, Ahmed M.; Jeljeli, Sami; More

Investigative Radiology. 58(6):413-419, June 2023.

Reduction of Gadolinium-Based Contrast Agents in MRI Using Convolutional Neural Networks and Different Input Protocols: Limited Interchangeability of Synthesized Sequences With Original Full-Dose Images Despite Excellent Quantitative Performance

Haase, Robert; Pinetz, Thomas; Bendella, Zeynep; More

Investigative Radiology. 58(6):420-430, June 2023.


Noninvasive 3-Dimensional 1H-Magnetic Resonance Spectroscopic Imaging of Human Brain Glucose and Neurotransmitter Metabolism Using Deuterium Labeling at 3T: Feasibility and Interscanner Reproducibility

Niess, Fabian; Hingerl, Lukas; Strasser, Bernhard; More

Investigative Radiology. 58(6):431-437, June 2023.