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This issue of the journal, as always, has many outstanding articles, representing cutting edge research and technology in diagnostic imaging. A study at 7 T demonstrates the utility at that field strength for increased spatial resolution in spectroscopy for the evaluation of multiple sclerosis lesions. A second excellent article explores visualization of the glymphatic system (CSF microcirculation) on MR following IV administration of gadolinium-based contrast agents. A third article describes advances in reduction of metal artifacts and improvement in dose efficiency using photon-counting detector CT in combination with tin filtration. The remaining papers explore important advances in tomoelastography, prostate imaging (specifically DWI), and T1- and T2*-mapping, as well as assessing robustness and reproducibility in Radiomics and adverse events with gadolinium chelate administration.

Current Issue Highlights

A Structured Survey on Adverse Events Occurring Within 24 Hours After Intravenous Exposure to Gadodiamide or Gadoterate Meglumine: A Controlled Prospective Comparison Study

Parillo, Marco; Sapienza, Martina; Arpaia, Francesco; More

Investigative Radiology. 54(4):191-197, April 2019.

Tomoelastography for the Evaluation of Pediatric Nonalcoholic Fatty Liver Disease

Hudert, Christian A.; Tzschätzsch, Heiko; Rudolph, Birgit; More

Investigative Radiology. 54(4):198-203, April 2019.

7 T Magnetic Resonance Spectroscopic Imaging in Multiple Sclerosis: How Does Spatial Resolution Affect the Detectability of Metabolic Changes in Brain Lesions?

Heckova, Eva; Strasser, Bernhard; Hangel, Gilbert J.; More

Investigative Radiology. 54(4):247-254, April 2019.