This issue of the journal, as always, has many outstanding articles, representing cutting edge research and technology in diagnostic imaging. Articles involving MR and CT are featured. Regarding MR, five articles highlight modern as well as newly available MR imaging techniques, focusing on their clinical utility. These papers address important issues in breast, liver and prostate imaging, looking as well at the importance of the time delay following gadolinium chelate administration for brain imaging and the use of synthetic MRI in pediatric brain studies. Two additional articles investigate issues regarding gadolinium deposition in the brain with the linear chelates, focusing primarily on gadodiamide (Omniscan). Regarding CT, one article is featured, investigating net water uptake as a quantitative biomarker of acute cerebral infarction.

Current Issue Highlights

Ring-Like Enhancement of Hepatocellular Carcinoma in Gadoxetic Acid–Enhanced Multiphasic Hepatic Arterial Phase Imaging With Differential Subsampling With Cartesian Ordering

Ichikawa, Shintaro; Motosugi, Utaroh; Oishi, Naoki; More

Investigative Radiology. 53(4):191-199, April 2018.

Effect of Age on High T1 Signal Intensity of the Dentate Nucleus and Globus Pallidus in a Large Population Exposed to Gadodiamide

Quattrocchi, Carlo Cosimo; Errante, Yuri; Mallio, Carlo Augusto; More

Investigative Radiology. 53(4):214-222, April 2018.

Increased Delay Between Gadolinium Chelate Administration and T1-Weighted Magnetic Resonance Imaging Acquisition Increases Contrast-Enhancing Tumor Volumes and T1 Intensities in Brain Tumor Patients

Piechotta, Paula L.; Bonekamp, David; Sill, Martin; More

Investigative Radiology. 53(4):223-228, April 2018.

Potential of Noncontrast Magnetic Resonance Imaging With Diffusion-Weighted Imaging in Characterization of Breast Lesions: Intraindividual Comparison With Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Baltzer, Pascal A.T.; Bickel, Hubert; Spick, Claudio; More

Investigative Radiology. 53(4):229-235, April 2018.