This issue of the journal, as always, has many outstanding articles, representing cutting edge research and technology in diagnostic imaging. Articles involving MR and CT are featured. Regarding MR, three articles highlight advances in imaging technique, for improved imaging of intracranial arteriovenous shunts, for the evaluation of (or absence thereof) spermatogenesis and utilizing DWI as a response marker in prostate cancer bone metastases. Three additional articles investigate issues concerning MR contrast media, one confirming the safety of Dotarem in pediatric subjects under 2 years of age, one demonstrating in the pediatric population the absence of dentate nucleus hyperintensity following Gadovist injection - and thus the stability of this macrocyclic agent, and the last evaluating the effects of perinatal exposure to GBCAs. Regarding CT, two articles are featured, both illustrating the utility of dual energy - one for improved visualization of brain edema and the other focusing on advanced calcium subtraction for improved luminal visualization.

​​​Investigative Radiology will publish a special issue on 'Contrast Media' in 2018. The focus is on current significant advances in knowledge regarding contrast media. Relevant topics include basic science investigations, clinical trials, innovative clinical applications, and safety. With regard to clinical papers, all organ and disease areas will be considered. Submitted manuscripts should significantly advance our knowledge concerning contrast media in MR, CT, or ultrasound.

Manuscripts are now being accepted for consideration. The deadline for submission is January 31, 2018. All papers will be subject to peer review by experts in the field and must comply with the Journal's Instructions for Authors.

Val M. Runge, MD, Editor-in-Chief, Investigative Radiology

Current Issue Highlights

Non contrast, Pseudo-Continuous Arterial Spin Labeling and Accelerated 3-Dimensional Radial Acquisition Intracranial 3-Dimensional Magnetic Resonance Angiography for the Detection ...

Schubert, Tilman; Clark, Zachary; Sandoval-Garcia, Carolina; More

Investigative Radiology. 53(2):80-86, February 2018.

Multiparametric Magnetic Resonance Imaging of Prostate Cancer Bone Disease: Correlation With Bone Biopsy Histological and Molecular Features

Perez-Lopez, Raquel; Nava Rodrigues, Daniel; Figueiredo, Ines; More

Investigative Radiology. 53(2):96-102, February 2018.

Heavily Calcified Coronary Arteries: Advanced Calcium Subtraction Improves Luminal Visualization and Diagnostic Confidence in Dual-Energy Coronary Computed Tomography Angiography

De Santis, Domenico; Jin, Kwang Nam; Schoepf, U. Joseph; More

Investigative Radiology. 53(2):103-109, February 2018.

Comparison of Unenhanced T1-Weighted Signal Intensities Within the Dentate Nucleus and the Globus Pallidus After Serial Applications of Gadopentetate Dimeglumine Versus Gadobutrol ...

Renz, Diane M.; Kümpel, Stefanie; Böttcher, Joachim; More

Investigative Radiology. 53(2):119-127, February 2018.