From the *Department of Radiology, and †Center for In Vivo Microscopy, Duke University Medical Center; ‡Department of Electrical and Computer Engineering, Duke University; §Department of Pulmonary and Critical Care Medicine, Duke University Medical Center; ∥Department of Biomedical Engineering, and ¶Medical Physics Graduate Program, Duke University, Durham, NC.
Received for publication April 29, 2016; and accepted for publication, after revision, July 5, 2016.
L.E. and B.D. are the guarantors of the integrity of the entire study and the contributors to the literature research. All the authors contributed to the study concepts/study design, data acquisition, or data analysis/interpretation; manuscript drafting or manuscript revision for important intellectual content; and approval of the final version of the submitted manuscript. T.H. and M.K. contributed to the clinical studies. M.H., S.S.K., M.S.F., and B.D. are the magnetic resonance experiments. M.H. and R.S.V. contributed to the statistical analysis. B.D., H.P.M., and R.S.V. contributed to the manuscript editing.
Conflicts of interest and sources of funding: This study was funded by Chiesi Pharmaceuticals, with additional support from NIH/NHLBI R01 HL105643 and the Duke Center for In Vivo Microscopy, an NIH/NIBIB National Biomedical Technology Resource Center (P41 EB015897). Lukas Ebner received financial funding by the Swiss National Science Foundation (grant P2SKP3_158645/1).
B.D. is a founder of Polarean, Inc.
Correspondence to: Lukas Ebner, MD, Department of Radiology, Duke University Medical Center, 3808, 2301 Erwin Road, Durham, NC 27710. E-mail: [email protected].