From the *Department of Radiological Sciences, Oncology, and Pathology, University of Rome “Sapienza”–Polo Pontino, Latina, Italy; †Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston; ‡Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, Sussex, England; §Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany; and ∥Department of Radiotherapy, University of Rome “Sapienza”, Rome, Italy.
Received for publication June 18, 2014; and accepted for publication, after revision, September 21, 2014.
Conflicts of interest and sources of funding: This study was funded by Associazione Italiana per la Ricerca sul Cancro, Investigator Grant 2013/14129.
Author B.G. is the scientific director of TexRAD Ltd (Somerset, England, United Kingdom), a company that develops and markets the texture analysis algorithm described in this manuscript. B.G. provided technical support for the texture analysis software used in this study. The author A.L. had control of the data and information submitted for publication, with no conflict of interest.
The other authors report no conflicts of interest.
Reprints: Andrea Laghi, MD, Department of Radiological Sciences, Oncology, and Pathology, University of Rome “Sapienza”–Polo Pontino, Via Franco Faggiana 34, Latina 04100, Italy. E-mail: [email protected].