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High Spatial Resolution Coronary Magnetic Resonance Angiography at 7 T: Comparison With Low Spatial Resolution Bright Blood Imaging

Bizino, Maurice B. MD*; Bonetti, Cosimo PhD; van der Geest, Rob J. PhD*; Versluis, Maarten J. PhD*; Webb, Andrew G. PhD*; Lamb, Hildo J. MD, PhD*

doi: 10.1097/RLI.0000000000000047
Original Articles
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Objectives The aim of this study was to compare bright blood high spatial resolution (HR) coronary magnetic resonance angiography (MRA) with low spatial resolution (LR) bright blood coronary MRA at 7 T.

Materials and Methods Twenty-four healthy volunteers underwent navigator-gated 3-dimensional imaging of the right coronary artery at 7 T using 2 sequences: HR bright blood and LR bright blood. Image postprocessing involved newly developed multiplanar reformatting to straighten the right coronary artery. Image quality was determined by vessel edge sharpness, signal-to-noise ratio, contrast-to-noise ratio, visible vessel length, and vessel diameter.

Results Vessel edge sharpness was statistically significantly higher in HR as compared with LR (0.57 ± 0.1 vs 0.46 ± 0.06; P < 0.001), at the cost of lower signal-to-noise ratio (HR, 32.9 ± 11.0 vs LR, 112.5 ± 48.9; P < 0.001) and contrast-to-noise ratio (HR, 17.9 ± 7.4 vs LR, 50.5 ± 26.1; P < 0.001). Visible vessel length and vessel diameter were similar for both sequences (P > 0.05).

Conclusions High spatial resolution bright blood coronary MRA at 7 T is feasible and improves vessel edge sharpness as compared with LR bright blood imaging.

From the Departments of *Radiology and †Cardiology, Leiden University Medical Center, Leiden, The Netherlands.

Received for publication July 23, 2013; and accepted for publication, after revision, January 22, 2014.

Maurice B. Bizino and Cosimo Bonetti contributed equally to this article.

Conflicts of interest and sources of funding: This work was supported by grant 01C-104 (project PREDICCt) from the Center for Translational Molecular Medicine, Eindhoven, the Netherlands.

The authors report no conflicts of interest.

Reprints: Maurice B. Bizino, MD, Department of Radiology, C3Q, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. E-mail: m.b.bizino@lumc.nl.

© 2014 by Lippincott Williams & Wilkins