The aim of this study was to compare bright blood high spatial resolution (HR) coronary magnetic resonance angiography (MRA) with low spatial resolution (LR) bright blood coronary MRA at 7 T.
Twenty-four healthy volunteers underwent navigator-gated 3-dimensional imaging of the right coronary artery at 7 T using 2 sequences: HR bright blood and LR bright blood. Image postprocessing involved newly developed multiplanar reformatting to straighten the right coronary artery. Image quality was determined by vessel edge sharpness, signal-to-noise ratio, contrast-to-noise ratio, visible vessel length, and vessel diameter.
Vessel edge sharpness was statistically significantly higher in HR as compared with LR (0.57 ± 0.1 vs 0.46 ± 0.06; P < 0.001), at the cost of lower signal-to-noise ratio (HR, 32.9 ± 11.0 vs LR, 112.5 ± 48.9; P < 0.001) and contrast-to-noise ratio (HR, 17.9 ± 7.4 vs LR, 50.5 ± 26.1; P < 0.001). Visible vessel length and vessel diameter were similar for both sequences (P > 0.05).
High spatial resolution bright blood coronary MRA at 7 T is feasible and improves vessel edge sharpness as compared with LR bright blood imaging.
From the Departments of *Radiology and †Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Received for publication July 23, 2013; and accepted for publication, after revision, January 22, 2014.
Maurice B. Bizino and Cosimo Bonetti contributed equally to this article.
Conflicts of interest and sources of funding: This work was supported by grant 01C-104 (project PREDICCt) from the Center for Translational Molecular Medicine, Eindhoven, the Netherlands.
The authors report no conflicts of interest.
Reprints: Maurice B. Bizino, MD, Department of Radiology, C3Q, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. E-mail: firstname.lastname@example.org.