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Psychosocial difficulties in patients with Parkinson’s disease

Schiavolin, Silviaa; Raggi, Albertoa; Quintas, Ruia,b; Cerniauskaite, Mildaa,c; Giovannetti, Ambra M.a,d; Covelli, Venusiaa,f; Romito, Luigie; Elia, Antonio E.e; Carella, Francescoe; Soliveri, Paolae; Leonardi, Matildea

International Journal of Rehabilitation Research: June 2017 - Volume 40 - Issue 2 - p 112–118
doi: 10.1097/MRR.0000000000000216
Original articles

The aim of this study was to report the most frequent psychosocial difficulties (PSDs) in patients with Parkinson disease (PD), to explore the relationship between PSDs, disability and quality of life (QoL), and to address the predictors of PSDs. Patients with PD were interviewed using a protocol composed of a questionnaire investigating PSDs (PARADISE 24), QoL, disability, comorbidity, and social support questionnaires, scales on resilience, personality traits, and empathy in physician. Most frequent PSDs were reported. Spearman’s correlation was used to address the relationship between PARADISE 24 and QoL and disability measures. Multiple linear regression was performed to investigate predictors of PARADISE 24. Eighty patients were enrolled: 40% women, mean age 61.2 years. The most frequent PSDs were related to cognitive and motor slowness, tiredness, sleeping, facing all things to do, depressive mood, and anxiety. PARADISE 24 were correlated with disability (ρ=0.831) and QoL (ρ=−0.685). Lower QoL, higher disability, early age at onset, and shorter disease duration were significant predictors of PSDs (adjusted R 2=0.762). PARADISE 24 is an easy to use questionnaire that could contribute toward describing the impact of PD on patients’ life more extensively, thus helping to define more tailored interventions.

aScientific Directorate, Neurology, Public Health, Disability Unit

bDepartment of Neurology VII - Clinical and Experimental Epileptology Unit

cDepartment of Neurosurgery, Radiotherapy Unit

dDepartment of Neuroimmunology and Neuromuscular Diseases

eDepartment of Neurology, Movement Disorders Unit, Neurological Institute C. Besta IRCCS Foundation

fDepartment of Psychology, e-Campus University, Milan, Italy

Correspondence to Silvia Schiavolin, PsyD, Neurology, Public Health, Disability Unit, Neurological Institute C. Besta IRCCS Foundation, Via Celoria 11, Milan 20133, Italy Tel: +39 02 2394 2949; fax: +39 02 2394 2442; e-mail:

Received June 13, 2016

Accepted January 3, 2017

Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.