Brief research reportsPrevalence and predictors of pain and fatigue after stroke: a population-based studyAppelros, PeterAuthor Information Department of Neurology, Örebro University Hospital, Örebro and the Neurotec Department, Karolinska Institutet, Stockholm, Sweden Correspondence and requests for reprints to P. Appelros, Department of Neurology, Örebro University Hospital, 701 85 Örebro, Sweden. Tel: +46 19 6022641; fax: +46 19 6116970; e-mail: [email protected] Sponsorship: This study was supported by grants from the Research Funds of Örebro County Council and the Swedish Stroke Association. Received 9 January 2006 Accepted 20 March 2006 International Journal of Rehabilitation Research: December 2006 - Volume 29 - Issue 4 - p 329-333 doi: 10.1097/MRR.0b013e328010c7b8 Buy Metrics Abstract Pain and fatigue are two often overlooked symptoms after stroke. Their prevalence and determinants are not well understood. In this study patients with first-ever stroke (n=377) were examined at baseline and after 1 year. General characteristics of the patients, as well as stroke type, stroke severity and risk factors were registered at baseline. After 1 year survivors (n=253) were examined with respect to residual impairment, disability, cognition and depression. They were asked whether they had experienced pain and/or fatigue which had started after the stroke, and which the patient felt to be stroke related. Twenty-eight patients (11%) had stroke-associated pain and 135 (53%) had stroke-associated fatigue. Pain was associated with depression and different manifestations of stroke severity, especially degree of paresis at baseline. Fatigue was more associated with physical disability. In univariate analysis, fatigue was also associated with sleep disturbances. In conclusion, it is important to be aware of the occurrence of pain and fatigue after stroke, because these symptoms are common, they impair quality of life and they are potentially treatable. Post-stroke depression may coexist with pain and fatigue. The detection of one symptom should lead to consideration of the others. Follow-up and individual assessment of stroke patients is crucial. Copyright © 2006 Wolters Kluwer Health, Inc. All rights reserved.