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Ovarian Involvement of Epithelioid Trophoblastic Tumor: A Case Report

Khunamornpong, Surapan M.D.; Settakorn, Jongkolnee M.D.; Sukpan, Kornkanok M.D.; Suprasert, Prapaporn M.D.; Siriaunkgul, Sumalee M.D.

International Journal of Gynecological Pathology: March 2011 - Volume 30 - Issue 2 - p 167–172
doi: 10.1097/PGP.0b013e3181f7124e

Epithelioid trophoblastic tumor (ETT) is an uncommon type of gestational trophoblastic neoplasia originating from the chorionic-type intermediate trophoblast. To our knowledge, ovarian involvement of ETT with initial presentation as an ovarian tumor has not been reported. A 32-year-old woman presented with a 9-cm left ovarian mass. No clinical evidence of uterine involvement was identified at diagnosis or follow-up. The patient had a previous history of hydatidiform mole treated with suctional curettage 5 years before. Ovarian involvement of ETT can be challenging to pathologists and may be potentially confused with ovarian epithelial carcinoma, particularly of clear cell differentiation.

Department of Pathology (S.K., J.S., K.S., S.S.)

Department of Obstetrics and Gynecology (P.S.), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

Address correspondence of to Surapan Khunamornpong, MD, Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. e-mail:

©2011International Society of Gynecological Pathologists