Langya virus: Slope of the iceberg for unexplored pathogens

Langya virus is a Henipavirus that has been found in shrews, bats, rats, and other small animals. Some studies also reveal that animals such as dogs and goats have natural antibodies to the Langya virus [1] . Furthermore, when exposed to bat urine, the virus may spread to other species such as horses or infect pigs [2] . As

Scientists investigated different animals for the presence of the Langya virus to determine the origins of the infection. They discovered viral evidence in goats and dogs, but the shrew was the principal source of the Langya virus. The virus was found in 27% of the shrew samples [8] .
The Langya virus's origin is still unknown. However, it is most likely passed from animal to human. Because the LayV virus RNA has been identified mostly in shrews, they may be its natural hosts [9] . The virus's contagiousness is determined by its spreadability and contagiousness. There are currently no facts about the human-to-human transfer. The scholars assert that the investigation's sample size is too small to detect any transmission. Conversely, no close-contact LayV transmission was found after tracking the contacts of nine patients with 15 close relatives [2] .
Those infected have reported the following symptoms: fever, fatigue, cough, anorexia, myalgia, nausea, headache, and vomiting. Furthermore, 35% of those contaminated had impaired liver function, and 8% of those infected had impaired renal function. According to doctors, the virus might cause a decrease in the number of platelets in the blood, significant damage to the kidneys and liver, and possibly death [5] . The Langya virus may produce symptoms such as fever, cough, fatigue, appetite decrease, muscle cramps, headache, and vomiting.
Serum seropositivity was found in 2% of goats and 5% of dogs in a sample of domestic animals [10] . Since the identification of this Henipavirus strain is novel, it serves to illustrate the ever-present danger of the creation of (new) infections. Due to the small sample size, further work is needed to fully grasp the disease's epidemiological and microbiological features. When it comes to combating potential pandemic infections, time is of the essence, making surveillance for their development a crucial tool.
Henipaviruses do not have any approved therapies. In animal experiments, experts have only tested a few antiviral alternatives. There is also no particular vaccination for the Langya virus. However, ribavirin may be an effective therapy. Doctors often use this medicine to treat viral infections that have no other therapeutic options. Ribavirin is effective against RNA viruses, including those that cause respiratory problems. Studies demonstrate that ribavirin is effective for both Hendra and Nipah viruses. The malaria medicine chloroquine may also be useful in

HIGHLIGHTS
• Langya virus is a Henipavirus that has been found in shrews, bats, and rats. • The Langya virus's origin is still unknown.
• Henipaviruses do not have any approved therapies.
• There is currently no evidence that the virus may spread from human to human.
treating these two conditions [1,11] . As a result, if necessary, these two medications may aid in the control of the Langya virus. This unusual virus is poorly understood, and experts predict that the number of verified cases will rise. There is currently no evidence that the virus may spread from human to human. More study is required to determine the virus's entire scope, its mode of dissemination, and whether it has already reached China and the surrounding region.

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Data statement
The data in this correspondence article is not sensitive in nature and is accessible in the public domain. The data is therefore available and not of a confidential nature.