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Caffeine-induced psychiatric manifestations: a review

Wang, Hee Ryung; Woo, Young Sup; Bahk, Won-Myong

International Clinical Psychopharmacology: July 2015 - Volume 30 - Issue 4 - p 179–182
doi: 10.1097/YIC.0000000000000076

The association between caffeine consumption and various psychiatric manifestations has long been observed. We present two cases that show the ability of caffeine to induce psychotic and manic symptoms, and we also review the extant literature on caffeine-induced psychiatric manifestations. On the basis of our own and others’ findings, we suggest that caffeine may be related to not only de-novo psychotic or mood symptoms but also to aggravation of pre-existing psychotic or mood disorders. We therefore suggest that caffeine consumption among patients with mood or psychotic symptoms should be assessed carefully in clinical practice as part of routine psychiatric evaluations.

Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea

Correspondence to Won-Myong Bahk, MD, PhD, Department of Psychiatry, Yeouido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, 10, 63 (yuksam)-ro, Yeongdeungpo-gu, Seoul 150-713, Korea Tel: +82 2 3779 1250; fax: +82 2 780 6577; e-mail:

Received January 15, 2015

Accepted March 12, 2015

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