REVIEW ARTICLECaffeine-induced psychiatric manifestations a reviewWang, Hee Ryung; Woo, Young Sup; Bahk, Won-MyongAuthor Information Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea Correspondence to Won-Myong Bahk, MD, PhD, Department of Psychiatry, Yeouido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, 10, 63 (yuksam)-ro, Yeongdeungpo-gu, Seoul 150-713, Korea Tel: +82 2 3779 1250; fax: +82 2 780 6577; e-mail: [email protected] Received January 15, 2015 Accepted March 12, 2015 International Clinical Psychopharmacology: July 2015 - Volume 30 - Issue 4 - p 179-182 doi: 10.1097/YIC.0000000000000076 Buy Metrics Abstract The association between caffeine consumption and various psychiatric manifestations has long been observed. We present two cases that show the ability of caffeine to induce psychotic and manic symptoms, and we also review the extant literature on caffeine-induced psychiatric manifestations. On the basis of our own and others’ findings, we suggest that caffeine may be related to not only de-novo psychotic or mood symptoms but also to aggravation of pre-existing psychotic or mood disorders. We therefore suggest that caffeine consumption among patients with mood or psychotic symptoms should be assessed carefully in clinical practice as part of routine psychiatric evaluations. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.