Original ArticlesThe clinical intervention choice for pediatric tic disorder patients from a tertiary children’s hospital in China: a large-scale retrospective study based on electronic medical recordsWang, Fanga; Ma, Zihanb; Li, Yinga; Wen, Fanga; Yu, Lipinga; Yan, Junjuana; Liu, Jingrana; Zhang, Jishuia,,*; Cui, Yonghuaa,,*Author Information aNational Center for Children’s Health, Beijing Children’s Hospital, Capital Medical University, Beijing, China bThe University of Hong Kong, Pok Fu Lam, Hong Kong *Jishui Zhang and Yonghua Cui contributed equally to this article. Received 27 January 2021 Accepted 30 March 2021 Supplemental Digital Content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's website, www.intclinpsychopharm.com Correspondence to Yonghua Cui, Beijing Children’s Hospital, Nanlishi Road 56, Beijing 100045, China, Tel/fax: +86010 59616161; e-mail: [email protected] International Clinical Psychopharmacology: July 2021 - Volume 36 - Issue 4 - p 208-213 doi: 10.1097/YIC.0000000000000362 Buy SDC Metrics Abstract Pharmacological intervention played an important role in the management of tic disorder. Large-scale prescription data for pediatric tic disorder patients in the real-world setting were scarce. The demographic and prescription data of tic disorder were extracted from the electronic medical records database of Beijing Children’s Hospital from 2018 to 2020. The intervention choice for outpatient pediatric tic disorder patients was analyzed. A total of 20 417 patients were included, 28.1% (n = 5028) of them did not receive any pharmacological treatment. Over 70% were prescribed with anti-tic medication. For children less than 6 years of age, clonidine adhesive patches (CAPs) and traditional Chinese medicine (TCM) were the common choice. With the age growing, the use of antipsychotics was on the rise; 22% (n = 3389) were prescribed for at least two anti-tic medication, and the most common medication combination group was tiapride and TCM (33.7%), followed by CAP and TCM (22.1%). The clinical intervention choice for tic disorder is highly individualized. The pharmacological choice was influenced by severity, duration of symptom, age, the acceptance of parents and other factors. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.