Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Compliance in schizophrenia spectrum disorders

the role of clinical pharmacist

Yalçin, Nadira; Ak, Sertaçb; Gürel, Şeref Canb; Çeliker, Ayçea

International Clinical Psychopharmacology: November 2019 - Volume 34 - Issue 6 - p 298–304
doi: 10.1097/YIC.0000000000000280
Original Articles

The inability of patients with psychiatric illness to achieve full compliance with treatment during the postdischarge period is a major problem. In this study, our aim was to evaluate whether drug education provided by a clinical pharmacist during discharging period has an effect on compliance. Forty adult patients diagnosed with psychotic disorders were included. A number of scales were used to evaluate the severity of illness, medication adverse effects and compliance. At time of discharge, it was emphasized to patients by a clinical pharmacist that medication compliance was important to prevent exacerbation or hospitalization. Six to eight weeks after discharge, patients were invited to be reevaluated using the same scales as those applied during hospitalization. There was a statistically significant increase in compliance after drug education (P < 0.001). A decrease in the baseline compliance score was associated with an increase in the total number of hospitalizations and the number of psychotropic drugs used. When the risk factors that may affect compliance were evaluated, akathisia was found to have the highest impact on compliance (P = 0.012). It is necessary to take advantage of counseling on medication use and to develop strategies in order to improve compliance in psychiatry.

aDepartment of Clinical Pharmacy, Faculty of Pharmacy

bDepartment of Psychiatry, Faculty of Medicine, Hacettepe University, Ankara, Turkey

Received 27 February 2019 Accepted 4 June 2019

Correspondence to Nadir Yalçin, MSc, Department of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara 06100, Turkey, Tel: +905356849300; fax: +903123114777; e-mail:

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.