Case ReportsNontyphoidal Salmonella Osteomyelitis in an Immunocompetent Adult Without Preceding SymptomsHanssen, Jaap L. J. MD∗; Anten, Sander MD∗; Stollenwerck, Guido MD†; Kuijpers, Laura M. F. MD, PhD∗ Author Information From the Departments of ∗Internal Medicine †Surgery, Alrijne Hospital, Leiderdorp, the Netherlands. Correspondence to: Jaap L. J. Hanssen, MD, Rijnstraat 79-3, 1079 GX, Amsterdam, the Netherlands. E-mail: [email protected]. The authors have no funding or conflicts of interest to disclose. Infectious Diseases in Clinical Practice: January 2021 - Volume 29 - Issue 1 - p e50-e52 doi: 10.1097/IPC.0000000000000922 Buy Metrics Abstract A 23-year-old man presented with a painful swelling of his left shin approximately 5 weeks after a very mild trauma. He had not experienced fever, abdominal pain, or diarrhea. Magnetic resonance images were compatible with chronic osteomyelitis. The cultures of the bone biopsy showed growth of Salmonella enterica serovar Enteritidis. Blood cultures remained sterile, there were no signs of a carrier state, and no immune deficiency could be found. After surgical debridement, the patient was treated with ceftriaxone and co-trimoxazole and later ciprofloxacin because of an allergic reaction. Nontyphoidal Salmonella osteomyelitis is rare in immunocompetent adults without a hemoglobinopathy. The treatment consists of surgical debridement and prolonged antibiotics. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.