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Acute Amebic Encephalitis in an Allogeneic Hematopoietic Stem-Cell Transplant Recipient

Still an Overlooked Diagnosis

Molina, Alfonso BS*; Winston, Drew J. MD; Haeri, Mohammad MD; Khanlou, Negar MD; Schiller, Gary J. MD

Infectious Diseases in Clinical Practice: July 2019 - Volume 27 - Issue 4 - p 188–190
doi: 10.1097/IPC.0000000000000744
Invited Original Article

Except for cerebral toxoplasmosis, parasitic central nervous system (CNS) infections are extremely rare in allogeneic hematopoietic stem-cell transplant recipients. We report an unusual case of acute amebic encephalitis in an allogeneic hematopoietic stem-cell transplant patient occurring more than 1 year after transplantation. Because the clinical presentation of amebic encephalitis can mimic other more common causes of CNS infection, the diagnosis should be considered whenever more common causes of CNS infection have been excluded.

From the *David Geffen School of Medicine, University of California, Los Angeles California;

Division of Hematology-Oncology, Department of Medicine, and

Neuropathology Section, Department of Pathology and Laboratory Medicine, Ronald Reagan UCLA Medical Center, Los Angeles, CA.

Correspondence to: Drew J. Winston, MD, Division of Hematology-Oncology, Department of Medicine, Ronald Reagan UCLA Center for the Health Sciences, Room 42-121 CHS, Los Angeles, CA 90095. E-mail:

The authors have no funding or conflicts of interest to disclose.

Online date: June 3, 2019

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