Case ReportsAll in The Name of Vanity An Unanticipated Outcome of Mycobacterium abscessus InfectionLi, Yan MD*; Spooner, Linda M. PharmD, BCPS (AQ-ID), FASHP, FCCP†; Abraham, George M. MD, MPH, FACP, FIDSA*‡Author Information From the *Department of Medicine, Saint Vincent Hospital; †Pharmacy Practice, Massachusetts College of Pharmacy and Health Sciences University School of Pharmacy; and ‡University of Massachusetts Medical School, Worcester, MA. Correspondence to: George M. Abraham, MD, MPH, FACP, FIDSA, Department of Medicine, Saint Vincent Hospital, University of Massachusetts Medical School, Worcester, MA. E-mail: [email protected]. The authors have no funding or conflicts of interest to disclose. Infectious Diseases in Clinical Practice: November 2018 - Volume 26 - Issue 6 - p 366-368 doi: 10.1097/IPC.0000000000000597 Buy Metrics Abstract We report a case of refractory skin abscesses caused by Mycobacterium abscessus resulting from cosmetic surgery. A 25-year-old woman developed recurrent cutaneous infection caused by M. abscessus after multiple cosmetic surgeries in the Dominican Republic. Despite of the removal of infected implants, she failed a 20-month treatment with azithromycin, cefoxitin, and amikacin. The patient presented to our institution 28 months after the initial surgeries and approximately 5 months after initiation of her latest antimicrobial regimen of azithromycin, imipenem, and amikacin. Here, she was restarted on cefoxitin 2 g daily, amikacin 750 mg daily, and azithromycin 1000 mg daily. She completed an additional 4 months (a total of 9 months) of therapy with complete clinical resolution. In conclusion, clinical suspicion of M. abscessus infection is essential for the diagnosis. Patient compliance is integral to a successful outcome because the treatment involves prolonged duration, continuous intravenous antibiotics, and multiple potential adverse effects. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.