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Nasofacial Destruction Due to Rhinoscleroma and Review of Other Causes

Beverido, Luis G. MD; Musenge, Kabanda Mary MD; Nanjappa, Sowmya MD; Ebersole, Russell MD; Greene, John N. MD, FACP

Infectious Diseases in Clinical Practice: January 2017 - Volume 25 - Issue 1 - p 48–53
doi: 10.1097/IPC.0000000000000454
Case Reports

Facial destruction is a process that can result in not only devastating physical changes but also significant psychological and emotional distress. Klebsiella rhinoscleromatis is noted to cause a chronic granulomatous inflammatory reaction called rhinoscleroma. It is seen worldwide exclusively in tropical and subtropical areas of underdeveloped countries associated with poor hygiene. It is thought that, because the United States has had a recent increase in immigration, the incidence of these infections will also increase. We present a case of biopsy-confirmed rhinoscleroma to increase the awareness of this long forgotten infection and discuss other causes that present similarly.

From the *Moffitt Cancer Center and Research Institute; †Internal Medicine, Moffitt Cancer Center and Research Institute; ‡University of South Florida Morsani College of Medicine, Tampa, FL; and §Pediatrics Department, Karolyn Kempton Memorial Christian Hospital, Togo, West Africa.

Correspondence to: John N. Greene, MD, FACP, Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, FOB-3, Tampa, FL 33612-9497. E-mail:

The authors have no funding or conflicts of interest to disclose.

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