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Triple Infections: Neurosyphilis and Neuroborreliosis in a Newly Diagnosed HIV-Positive Man and Review of the Literature

Chen, Ting-Yi MD, MPH; Zhou, Di BS; Sterling, Stephanie A. MD, MPH

Infectious Diseases in Clinical Practice: July 2014 - Volume 22 - Issue 4 - p e66–e68
doi: 10.1097/IPC.0b013e3182a0ea85
Case Reports

In this brief report, we describe a previous healthy 52-year-old man who presented with a 4-year progressive cognitive decline. Serum and cerebrospinal fluid immunoassays confirmed the diagnosis of neurosyphilis and neuroborreliosis; he also tested positive for human immunodeficiency virus. Treatment with aqueous penicillin G and antiretroviral therapy resulted in excellent outcome.

From the New York University School of Medicine, New York, NY.

Correspondence to: Ting-Yi Chen, MD, MPH, New York University School of Medicine, New York. E-mail:

Authors have no funding or conflicts of interest to disclose.

There was no pharmaceutical grant support for this study or outside influence on study concept, design, data analysis, and preparation of manuscript.

© 2014 by Lippincott Williams & Wilkins.