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Acute Fibrinous and Organizing Pneumonia After Mycoplasma pneumoniae Infection

Kassir, Mohammad M. MD*†; Tran, Truc C. BS*†; Bagdasarian, Natasha MD, MPH

Infectious Diseases in Clinical Practice: July 2014 - Volume 22 - Issue 4 - p e63–e65
doi: 10.1097/IPC.0b013e3182a0e981
Case Reports

Acute fibrinous and organizing pneumonia (AFOP) is a recently described and relatively rare type of interstitial lung disease. It is defined by a histologic pattern of intra-alveolar fibrin deposition, along with patchy organizing pneumonia. We report the case of a 53-year-old white woman who complained of fevers, chills, fatigue, shortness of breath, and nonproductive cough for 1 week. She was diagnosed with AFOP on peripheral lung biopsy. Serology revealed a simultaneous or recent infection with Mycoplasma pneumoniae. Although M. pneumoniae infection commonly presents as pneumonia of gradual and insidious onset, it can rarely have a fulminant presentation. This report adds AFOP to the list of rare complications of M. pneumoniae infection.

From the *Wayne State University School of Medicine, Detroit; and †Oakwood Hospital & Medical Center, Dearborn, MI.

Correspondence to: Natasha Bagdasarian MD, MPH, Department of Medical Education, Oakwood Hospital & Medical Center, 18101 Oakwood Blvd, Dearborn, MI 48124. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2014 by Lippincott Williams & Wilkins.