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Bornholm Disease: Case Report and a Review of the Literature

Ivan, Yaron MD*; Kelly, Brendan P. MD

Infectious Diseases in Clinical Practice: March 2014 - Volume 22 - Issue 2 - p 75–77
doi: 10.1097/IPC.0b013e318298b611
Review Articles

Bornholm disease is an uncommon cause of sudden-onset, severe, abdominal pain in adolescents and young adults caused by Coxsackievirus infection. Physicians who care for this patient population should consider Bornholm disease when presented with an acute abdomen or when other serious causes of abdominal pain have been ruled out. Typically, patients with this presentation progress to have pleuritic chest pain associated with a normal chest radiograph. Obtaining Coxsackievirus titers can help confirm the diagnosis. With this case presentation and review of the literature, we demonstrate the varied clinical presentation of Bornholm disease in adolescents and young adults.

From the *Tufts University School of Medicine, and †Medicine and Pediatrics, Tufts University School of Medicine, Boston MA.

Correspondence to: Yaron Ivan, MD, Baystate Medical Center, 759 Chestnut St, Springfield, MA. 01199. E-mail:;

The authors have no funding or conflicts of interest to disclose.

© 2014 by Lippincott Williams & Wilkins.