Coccidioidomycosis is an endemic fungal disease that can cause a primary pulmonary, progressive pulmonary, or disseminated disease that can be severe in patients on tumor necrosis factor α inhibitors for the treatment of a variety of autoimmune and granulomatous disorders. Here, we report a complicated case of disseminated coccidioidomycosis with rare ocular involvement after a possible immune reconstitution inflammatory syndrome in a 51-year-old man on infliximab for the treatment of rheumatoid arthritis.
From the *College of Medicine, University of South Florida; †Division of Infectious Diseases, Moffitt Cancer Center, and ‡Clinical Microbiology and Virology Laboratories, Moffitt Cancer Center, Tampa, FL.
Correspondence to: John N. Greene, MD, FACP, Division of Infectious Diseases, Moffitt Cancer Center, University of South Florida College of Medicine, 12902 Magnolia Dr, FOB-3, Tampa, FL 33612-9497. E-mail: email@example.com.
Ani Chawdry and Lyudmila Shumyak are fourth-year medical students of the University of South Florida College of Medicine.
The authors have no conflicts of interest to disclose.