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The First Case Report of Staphylococcus intermedius Pneumonia in a Patient With Cystic Fibrosis

Dumrongmongcolgul, Nat MD; Mankongpaisarnrung, Charoen MD; Kanu, Adaobi MD; Sutamtewagul, Grerk MD; Winn, Richard MD; Desai, Vipul MD

Infectious Diseases in Clinical Practice: November 2013 - Volume 21 - Issue 6 - p 392–394
doi: 10.1097/IPC.0b013e31827e1319
Case Report

Staphylococcus intermedius is a coagulase and gram-positive zoonotic organism, which is common in cats and dogs. It has rarely been identified as a human pathogen. We report a case of S intermedius pneumonia in a woman with cystic fibrosis. She presented with submassive hemoptysis, which evolved into respiratory failure and acute respiratory distress syndrome, ultimately requiring mechanical ventilation. Initial empiric therapy with vancomycin was inadequate; linezolid and ceftaroline were substituted. Improvement was observed; she recovered and was discharged with a temporary tracheostomy. To our knowledge, this is the first case report of community-acquired pneumonia due to S intermedius occurring in cystic fibrosis. Clinically, it seemed that vancomycin was inactive.

From the Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX.

Correspondence to: Vipul Desai, MD, Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th St, Lubbock, TX 79430. E-mail:

The authors have no funding or conflicts of interest to disclose.

This manuscript has not been published and is not under consideration for publication elsewhere. All the authors have read the manuscript and have approved this submission.

© 2013 by Lippincott Williams & Wilkins.