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Endogenous Fusarium Endophthalmitis in Hematologic Malignancy: Short Case Series and Review of Literature

Malavade, Sharad Suryakant DNB (Ophth), MPH*†; Mai, Mo MD; Pavan, Peter MD*; Nasr, Georgina MD§; Sandin, Ramon MD, MS; Greene, John MD§∥

Infectious Diseases in Clinical Practice: January 2013 - Volume 21 - Issue 1 - p 6–11
doi: 10.1097/IPC.0b013e31826ba107
Review Articles

Patients with hematologic malignancy are in a state of immunocompromise either due to the disease or as result of treatment. They are at risk for opportunistic fungal infections. The usual agents implicated are Aspergillus and Fusarium species. Patients with infected skin lesions are at risk of endogenous dissemination, and the eye can be one of the potential sites of infection due to hematogenous Fusarium dissemination. We describe 3 immunocompromised patients with hematologic malignancy who developed endogenous fusarial endophthalmitis.

From the Departments of *Ophthalmology and †Global Health, University of South Florida, Tampa, FL; ‡Ross University School of Medicine, Commonwealth of Dominica, West Indies; §Department of Infectious Diseases, University of South Florida; and ∥Moffitt Cancer Center, Tampa, FL.

Correspondence to: John Greene, MD, Infectious Diseases and Infection Prevention, Moffitt Cancer Center, 12902 Magnolia Dr, Mailstop FOB-3, Tampa, FL 33612. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2013 Lippincott Williams & Wilkins, Inc.