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Adenovirus Esophagitis in an HIV-Positive Patient: Extraordinary Presentation of a Common Viral Infection

Boumans, Dennis MD*; Kootstra, Gert-Jan MD; van Olffen, Gerard H. MD; Brinkhuis, Mariël PhD§; ten Napel, Chris H.H. PhD

Infectious Diseases in Clinical Practice: September 2012 - Volume 20 - Issue 5 - p 354–356
doi: 10.1097/IPC.0b013e318248f0f5
Case Reports

Human adenovirus mostly causes self-limiting diseases but may also induce serious complications in healthy as well as immunocompromised patients. We report a case of a 40-year-old homosexual man with chronic untreated human immunodeficiency virus infection, presenting with dysphagia because of an ulcerative esophagitis caused by human adenovirus. Adenovirus infection as a cause of esophagitis has not been reported before, so it should be considered in a differential diagnosis of dysphagia, especially in the context of human immunodeficiency virus.

From the *Department of Internal Medicine, Ziekenhuisgroep Twente, Almelo; and †Departments of Internal Medicine, and ‡Gastroenterology and Liver Diseases, Medisch Spectrum Twente; and §Laboratory for Pathology East Netherlands, Enschede, The Netherlands.

Correspondence to: Dennis Boumans, MD, Department of Internal Medicine, Ziekenhuisgroep Twente Almelo, PO Box 7600, Zilvermeeuw 1, 7600 SZ Almelo, The Netherlands. E-mail:

The authors have no funding or conflicts of interest to disclose.

The authors alone are responsible for the content and writing of the article.

© 2012 Lippincott Williams & Wilkins, Inc.