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Chorioamnionitis Caused by Methicillin-Resistant Staphylococcus aureus: Report of a Case and Review of the Literature

Healy, Amber M. DO*; Tamirisa, Anita DO; Myers, Joseph P. MD

Infectious Diseases in Clinical Practice: July 2012 - Volume 20 - Issue 4 - p 242–244
doi: 10.1097/IPC.0b013e31823c49e5
Review Articles

Methicillin-resistant Staphylococcus aureus is an emerging pathogen in hospital nurseries and maternity units but has remained an unusual cause of invasive peripartum disease including chorioamnionitis. A 20-year-old woman at 30 weeks’ estimated gestational age presented to the hospital with fever, premature rupture of membranes, vaginal bleeding, and shortly spaced uterine contractions. Placental abruption was diagnosed, and emergency cesarean section was performed. A 1502-g infant girl was delivered with 1- and 5-minute Apgar scores of 8 and 8. Placenta was sent for culture and pathological examination. Placental culture revealed pure growth of methicillin-resistant S. aureus, and pathological examination showed chorioamnionitis, funisitis, and chorionic plate vessel vasculitis. We review our patient and all previously reported patients and present their epidemiology, manifestations, microbiologic data, and clinical outcomes.

From the *Internal Medicine Residency and †Obstetrics and Gynecology Residency, Summa Health System/Northeast Ohio Medical University Program, Akron; and ‡Department of Medicine, Summa Health System and Northeast Ohio Medical University, Rootstown, OH.

Correspondence to: Joseph P. Myers, MD, Department of Medicine, Summa Akron City/St Thomas Hospitals, 55 Arch St, Ste. 1-A, Akron, OH 44304. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2012 Lippincott Williams & Wilkins, Inc.