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Staphylococcus lugdunensis Tricuspid Valve Endocarditis Associated With Home Hemodialysis Therapy: Report of a Case and Review of the Literature

Conner, Ronald C. MD*; Byrnes, Timothy J. DO; Clough, Lynn A. PhD; Myers, Joseph P. MD

Infectious Diseases in Clinical Practice: May 2012 - Volume 20 - Issue 3 - p 182–183
doi: 10.1097/IPC.0b013e318245d4f1
Review Articles

Home hemodialysis is used by 1.0% of dialysis patients with end-stage renal disease in the United States. Patients undergoing home hemodialysis have lower morbidity and mortality rates than those using center-based hemodialysis or home peritoneal dialysis. We report the first patient on home hemodialysis with Staphylococcus lugdunensis endocarditis and review the unusual properties of this aggressive coagulase-negative Staphylococcus. We report a 45-year-old man who developed S. lugdunensis infective endocarditis while on home hemodialysis. Endocarditis complicating home hemodialysis is rare, and endocarditis complicating home hemodialysis due to S. lugdunensis has not been previously reported. S. lugdunensis is a coagulase-negative Staphylococcus that may cause rapid onset of symptoms and rapid destruction of tissue. Its incidence may be underestimated, and its presence may be missed because some clinical microbiology laboratories do not routinely speciate coagulase-negative staphylococci isolated in culture from clinical specimens.

From the *Department of Medicine, University of Toledo Health Sciences Campus, Toledo; and †Internal Medicine Residency, Summa Health System/Northeast Ohio Medical University Program, Akron; and ‡Department of Medicine, Summa Health System and Northeast Ohio Medical University, Rootstown, OH.

Correspondence to: Joseph P. Myers, MD, Department of Medicine, Summa Akron City/St. Thomas Hospitals, 55 Arch St, Suite 1-A, Akron, OH 44304. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2012 Lippincott Williams & Wilkins, Inc.