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Pasteurella multocida Supraglottitis Resulting in Bacteremia and Vascular Homograft Infection

DeFreest, Lori A. MD, PhD*; Tobin, Ellis H. MD†‡; Harrington, Susan M. PhD§; Wang, Danny C. MD, MPH; Massey, H. Todd MD

Infectious Diseases in Clinical Practice: January 2012 - Volume 20 - Issue 1 - p 88–90
doi: 10.1097/IPC.0b013e31821d338e
Case Reports

Pasteurella multocida is a common cause of soft tissue infections in humans and usually results from a bite by a domestic or wild animal. Pasteurella supraglottitis is rare and likely results from a non-bite animal exposure. We report a case of P. multocida supraglottitis resulting in bacteremia and seeding of a vascular homograft resulting in pseudoaneurysm formation. After surgical repair of the graft and 6 weeks of postoperative antibiotic therapy, the patient resumed normal activities and has continued to do well after 1 year of follow-up. This case illustrates the potential for P. multocida to cause non-bite–associated infections. This is the first report of this zoonotic infection involving a vascular homograft.

From the *Departments of Surgery and †Medicine, Albany Medical College; ‡Upstate Infectious Diseases Associates; §Clinical Microbiology Laboratory, ∥Department of Radiology, Albany Medical College, Albany, NY; and ¶Division of Cardiothoracic Surgery, University of Rochester School of Medicine, Strong Memorial Hospital, Rochester, NY.

Correspondence to: Ellis H. Tobin, MD, Upstate Infectious Diseases Associates, 567 New Scotland Ave, Albany, NY 12208. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2012 Lippincott Williams & Wilkins, Inc.