Coccidioidomycosis is a fungal infection endemic to the southwestern United States as well as the regions of Mexico, Central America, and South America. Although the majority of infected persons experience self-limited respiratory infections, severe pneumonias and extrapulmonary disseminated disease are responsible for considerable morbidity and mortality, particularly among those with occupational exposures, immunosuppression, and certain high-risk ethnic groups. In this review, we discuss the epidemiology as well as the diagnosis and current therapy of this protean illness.
From the *Division of Infectious Diseases, Naval Medical Center, San Diego; and †Department of Deployment Health, Naval Health Research Center, San Diego, CA.
Correspondence to: Ryan Maves, MD, Infectious Diseases Division, Naval Medical Center San Diego, 34800 Bob Wilson Dr, Ste. 5, San Diego, CA 92134-1005. E-mail: firstname.lastname@example.org.
Both authors contributed to the content of the manuscript and concurred with the decision to submit it for publication.
One of the authors (R.C.M.) is an employee of the US Government. This work was prepared as part of their duties. Title 17 U.S.C. §105 provides that “Copyright protection under this title is not available for any work of the US Government.” Title 17 U.S.C. §101 defines a US Government work as a work prepared by a military service member or official employee of the US Government as part of that person’s official duties.
The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the US Government.
The authors have no funding or conflicts of interest to disclose.