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A Case of Coccidioides Synovitis of the Knee Presents Clinically as Pigmented Villonodular Synovitis

Stein, Mathew I. MD*; Palumbo, Brian T. MD*; Bui, Marilyn M. MD, PhD; Sandin, Ramon L. MD, MS; Greene, John MD; Letson, Gordon Douglas MD§

Infectious Diseases in Clinical Practice: November 2011 - Volume 19 - Issue 6 - p 439-441
doi: 10.1097/IPC.0b013e318210fdd6
Case Reports

Few cases of primary coccidioides synovitis of the knee have been reported in the literature, almost all of which have been before the widespread use of magnetic resonance imaging. We describe the case of a man presenting with findings classically associated with pigmented villonodular synovitis who was subsequently diagnosed with primary coccidioidal synovitis of the knee. This case outlines the clinical, radiographic, and pathological characteristics of coccidioidal synovitis that has yet to be outlined in the literature.

From the *Department of Orthopaedic Surgery, University of South Florida, Tampa, FL; †Department of Anatomic Pathology, Sarcoma Program, ‡Department of Infectious Diseases, and §Department of Orthopaedic Surgery,Sarcoma Program, Moffitt Cancer Center, Tampa, FL.

Correspondence to: Mathew Stein, MD, Department of Orthopaedics and Sports Medicine, University of South Florida, 13220 USF Laurel Dr, MDF 5th Floor, Tampa, FL 33613. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2011 Lippincott Williams & Wilkins, Inc.